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This orthogroup contains 235 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 235 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12900 | MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| Pfam | PF04005 | Hus1 | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0000077 Biological Process | DNA damage checkpoint signaling | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0000723 Biological Process | telomere maintenance | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0000724 Biological Process | double-strand break repair via homologous recombination | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0006289 Biological Process | nucleotide-excision repair | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0030896 Cellular Component | checkpoint clamp complex | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0031573 Biological Process | mitotic intra-S DNA damage checkpoint signaling | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0033314 Biological Process | mitotic DNA replication checkpoint signaling | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0035861 Cellular Component | site of double-strand break | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0044778 Biological Process | meiotic DNA integrity checkpoint signaling | 215 / 235 | 91.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0005730 Cellular Component | nucleolus | 197 / 235 | 83.8% | 91.6% of 215 | ≥80% support |
| KEGG | K10903 | HUS1 — DNA repair and recombination proteins | 183 / 235 | 77.9% | 99.5% of 184 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_023464-T1 | KAJ7384136.1 | DNA damage checkpoint control protein [Desmophyllum pertusum] | Q8BQY8 Checkpoint protein HUS1 OS=Mus musculus OX=10090 GN=Hus1 PE= | JBrowse |
