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This orthogroup contains 224 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 224 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12800 | CDC37-RELATED | 203 / 224 | 90.6% | 100.0% of 203 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 203 / 224 | 90.6% | 100.0% of 203 | ≥80% support |
| GO | GO:0006457 Biological Process | protein folding | 203 / 224 | 90.6% | 100.0% of 203 | ≥80% support |
| GO | GO:0031072 Molecular Function | heat shock protein binding | 203 / 224 | 90.6% | 100.0% of 203 | ≥80% support |
| GO | GO:0050821 Biological Process | protein stabilization | 203 / 224 | 90.6% | 100.0% of 203 | ≥80% support |
| GO | GO:0051082 Molecular Function | unfolded protein binding | 203 / 224 | 90.6% | 100.0% of 203 | ≥80% support |
| GO | GO:0051087 Molecular Function | protein-folding chaperone binding | 203 / 224 | 90.6% | 100.0% of 203 | ≥80% support |
| Pfam | PF08565 | CDC37_M — Cdc37 Hsp90 binding domain | 178 / 224 | 79.5% | 89.0% of 200 | ≥50% support |
| Pfam | PF08564 | CDC37_C — Cdc37 C terminal domain | 176 / 224 | 78.6% | 88.0% of 200 | ≥50% support |
| Pfam | PF03234 | CDC37_N — Cdc37 N terminal kinase binding | 160 / 224 | 71.4% | 80.0% of 200 | ≥50% support |
| GO | GO:0019901 Molecular Function | protein kinase binding | 167 / 224 | 74.6% | 82.3% of 203 | ≥50% support |
| KEGG | K09554 | CDC37 — Glycosaminoglycan binding proteins | 164 / 224 | 73.2% | 98.8% of 166 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_008114-T1 | KAJ7337947.1 | hsp90 co-chaperone Cdc37 [Desmophyllum pertusum] | Q16543 Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE | JBrowse |
