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This orthogroup contains 195 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 195 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR19278 | OROTATE PHOSPHORIBOSYLTRANSFERASE | 168 / 195 | 86.2% | 97.1% of 173 | ≥80% support |
| Pfam | PF00215 | OMPdecase — Orotidine 5'-phosphate decarboxylase / HUMPS family | 156 / 195 | 80.0% | 94.6% of 165 | ≥80% support |
| GO | GO:0004588 Molecular Function | orotate phosphoribosyltransferase activity | 173 / 195 | 88.7% | 100.0% of 173 | ≥80% support |
| GO | GO:0006222 Biological Process | UMP biosynthetic process | 168 / 195 | 86.2% | 97.1% of 173 | ≥80% support |
| GO | GO:0019856 Biological Process | pyrimidine nucleobase biosynthetic process | 168 / 195 | 86.2% | 97.1% of 173 | ≥80% support |
| GO | GO:0004590 Molecular Function | orotidine-5'-phosphate decarboxylase activity | 163 / 195 | 83.6% | 94.2% of 173 | ≥80% support |
| GO | GO:0006207 Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | 160 / 195 | 82.1% | 92.5% of 173 | ≥80% support |
| Pfam | PF00156 | Pribosyltran — Phosphoribosyl transferase domain | 108 / 195 | 55.4% | 65.5% of 165 | ≥50% support |
| GO | GO:0044205 Biological Process | 'de novo' UMP biosynthetic process | 153 / 195 | 78.5% | 88.4% of 173 | ≥50% support |
| GO | GO:0006221 Biological Process | pyrimidine nucleotide biosynthetic process | 141 / 195 | 72.3% | 81.5% of 173 | ≥50% support |
| KEGG | K13421 | UMPS — Drug metabolism - other enzymes | 143 / 195 | 73.3% | 91.1% of 157 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_037978-T1 | KAJ7381958.1 | hypothetical protein OS493_037978 [Desmophyllum pertusum] | P13439 Uridine 5'-monophosphate synthase OS=Mus musculus OX=10090 G | JBrowse |