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This orthogroup contains 177 genes from 123 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 177 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12708 | DNA POLYMERASE EPSILON SUBUNIT B | 155 / 177 | 87.6% | 99.4% of 156 | ≥80% support |
| Pfam | PF04042 | DNA_pol_E_B — DNA polymerase alpha/epsilon subunit B | 148 / 177 | 83.6% | 97.4% of 152 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 155 / 177 | 87.6% | 99.4% of 156 | ≥80% support |
| GO | GO:0006261 Biological Process | DNA-templated DNA replication | 155 / 177 | 87.6% | 99.4% of 156 | ≥80% support |
| GO | GO:0008622 Cellular Component | epsilon DNA polymerase complex | 155 / 177 | 87.6% | 99.4% of 156 | ≥80% support |
| GO | GO:0042276 Biological Process | error-prone translesion synthesis | 155 / 177 | 87.6% | 99.4% of 156 | ≥80% support |
| GO | GO:0006260 Biological Process | DNA replication | 148 / 177 | 83.6% | 94.9% of 156 | ≥80% support |
| Pfam | PF12213 | Dpoe2NT — DNA polymerases epsilon N terminal | 138 / 177 | 78.0% | 90.8% of 152 | ≥50% support |
| KEGG | K02325 | POLE2 — DNA repair and recombination proteins | 135 / 177 | 76.3% | 99.3% of 136 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_021634-T1 | KAJ7330706.1 | DNA polymerase epsilon subunit 2 [Desmophyllum pertusum] | P56282 DNA polymerase epsilon subunit 2 OS=Homo sapiens OX=9606 GN= | JBrowse |
