← Back to the gene family browser
This orthogroup contains 161 genes from 104 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 161 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46139 | ALKALINE CERAMIDASE | 156 / 161 | 96.9% | 100.0% of 156 | ≥80% support |
| Pfam | PF05875 | Ceramidase | 157 / 161 | 97.5% | 100.0% of 157 | ≥80% support |
| GO | GO:0006672 Biological Process | ceramide metabolic process | 157 / 161 | 97.5% | 100.0% of 157 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 157 / 161 | 97.5% | 100.0% of 157 | ≥80% support |
| GO | GO:0016811 Molecular Function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 157 / 161 | 97.5% | 100.0% of 157 | ≥80% support |
| GO | GO:0046514 Biological Process | ceramide catabolic process | 156 / 161 | 96.9% | 99.4% of 157 | ≥80% support |
| KEGG | K01441 | ACER1_2, ASAH3 — Sphingolipid signaling pathway | 148 / 161 | 91.9% | 99.3% of 149 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_032184-T1 | KAJ7389328.1 | Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid [Desmophyllum pertusum] | Q5QJU3 Alkaline ceramidase 2 OS=Homo sapiens OX=9606 GN=ACER2 PE=1 | JBrowse |
| Lophelia pertusa | OS493_032185-T1 | KAJ7389329.1 | Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid [Desmophyllum pertusum] | Q5QJU3 Alkaline ceramidase 2 OS=Homo sapiens OX=9606 GN=ACER2 PE=1 | JBrowse |
