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This orthogroup contains 151 genes from 83 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 151 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43128 | L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) | 144 / 151 | 95.4% | 100.0% of 144 | ≥80% support |
| Pfam | PF02866 | Ldh_1_C — lactate/malate dehydrogenase, alpha/beta C-terminal domain | 138 / 151 | 91.4% | 96.5% of 143 | ≥80% support |
| Pfam | PF00056 | Ldh_1_N — lactate/malate dehydrogenase, NAD binding domain | 132 / 151 | 87.4% | 92.3% of 143 | ≥80% support |
| GO | GO:0004459 Molecular Function | L-lactate dehydrogenase activity | 144 / 151 | 95.4% | 100.0% of 144 | ≥80% support |
| GO | GO:0006089 Biological Process | lactate metabolic process | 144 / 151 | 95.4% | 100.0% of 144 | ≥80% support |
| GO | GO:0006090 Biological Process | pyruvate metabolic process | 144 / 151 | 95.4% | 100.0% of 144 | ≥80% support |
| GO | GO:0016616 Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 144 / 151 | 95.4% | 100.0% of 144 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 142 / 151 | 94.0% | 98.6% of 144 | ≥80% support |
| GO | GO:0019752 Biological Process | carboxylic acid metabolic process | 136 / 151 | 90.1% | 94.4% of 144 | ≥80% support |
| GO | GO:0016491 Molecular Function | oxidoreductase activity | 132 / 151 | 87.4% | 91.7% of 144 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 106 / 151 | 70.2% | 73.6% of 144 | ≥50% support |
| KEGG | K00016 | LDH, ldh — Exosome | 110 / 151 | 72.9% | 92.4% of 119 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_027046-T1 | KAJ7327356.1 | L-lactate dehydrogenase A chain [Desmophyllum pertusum] | Q27888 L-lactate dehydrogenase OS=Caenorhabditis elegans OX=6239 GN | JBrowse |
