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This orthogroup contains 846 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 846 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22826 | RHO GUANINE EXCHANGE FACTOR-RELATED | 714 / 846 | 84.4% | 94.7% of 754 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 718 / 846 | 84.9% | 94.7% of 758 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 716 / 846 | 84.6% | 94.5% of 758 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 695 / 846 | 82.2% | 91.7% of 758 | ≥80% support |
| Pfam | PF00621 | RhoGEF | 641 / 846 | 75.8% | 87.8% of 730 | ≥50% support |
| Pfam | PF00041 | fn3 — Fibronectin type III domain | 599 / 846 | 70.8% | 82.1% of 730 | ≥50% support |
| Pfam | PF00435 | Spectrin | 553 / 846 | 65.4% | 75.8% of 730 | ≥50% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 483 / 846 | 57.1% | 66.2% of 730 | ≥50% support |
| Pfam | PF07653 | SH3_2 — Variant SH3 domain | 435 / 846 | 51.4% | 59.6% of 730 | ≥50% support |
| Pfam | PF07679 | I-set | 429 / 846 | 50.7% | 58.8% of 730 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 485 / 846 | 57.3% | 64.0% of 758 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 484 / 846 | 57.2% | 63.9% of 758 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 484 / 846 | 57.2% | 63.9% of 758 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Millepora alcicornis | ENSCIQP00000010890.1 | XP_047137674.1 | triple functional domain protein isoform X4 [Hydra vulgaris] | – | JBrowse |
| Millepora alcicornis | ENSCIQP00000013308.1 | XP_047137674.1 | triple functional domain protein isoform X4 [Hydra vulgaris] | Q1LUA6 Triple functional domain protein OS=Danio rerio OX=7955 GN=t | JBrowse |
| Millepora alcicornis | ENSCIQP00000013338.1 | XP_047137672.1 | triple functional domain protein isoform X2 [Hydra vulgaris] | P97924 Kalirin OS=Rattus norvegicus OX=10116 GN=Kalrn PE=1 SV=3 | JBrowse |
| Millepora alcicornis | ENSCIQP00000013341.1 | XP_047137673.1 | triple functional domain protein isoform X3 [Hydra vulgaris] | – | JBrowse |
| Millepora alcicornis | ENSCIQP00000013346.1 | XP_047137673.1 | triple functional domain protein isoform X3 [Hydra vulgaris] | Q1LUA6 Triple functional domain protein OS=Danio rerio OX=7955 GN=t | JBrowse |
| Millepora alcicornis | ENSCIQP00000014261.1 | XP_047137674.1 | triple functional domain protein isoform X4 [Hydra vulgaris] | O75962 Triple functional domain protein OS=Homo sapiens OX=9606 GN= | JBrowse |
