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This orthogroup contains 314 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 314 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10670 | DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A | 268 / 314 | 85.4% | 99.6% of 269 | ≥80% support |
| GO | GO:0003887 Molecular Function | DNA-directed DNA polymerase activity | 273 / 314 | 86.9% | 99.6% of 274 | ≥80% support |
| GO | GO:0006260 Biological Process | DNA replication | 273 / 314 | 86.9% | 99.6% of 274 | ≥80% support |
| GO | GO:0000278 Biological Process | mitotic cell cycle | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0045004 Biological Process | DNA replication proofreading | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0008622 Cellular Component | epsilon DNA polymerase complex | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0008310 Molecular Function | single-stranded DNA 3'-5' DNA exonuclease activity | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0006297 Biological Process | nucleotide-excision repair, DNA gap filling | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0006287 Biological Process | base-excision repair, gap-filling | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0006272 Biological Process | leading strand elongation | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 268 / 314 | 85.4% | 97.8% of 274 | ≥80% support |
| Pfam | PF08490 | DUF1744 | 199 / 314 | 63.4% | 79.0% of 252 | ≥50% support |
| Pfam | PF03104 | DNA_pol_B_exo1 — DNA polymerase family B, exonuclease domain | 185 / 314 | 58.9% | 73.4% of 252 | ≥50% support |
| Pfam | PF00136 | DNA_pol_B — DNA polymerase family B | 175 / 314 | 55.7% | 69.4% of 252 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 203 / 314 | 64.7% | 74.1% of 274 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 202 / 314 | 64.3% | 73.7% of 274 | ≥50% support |
| GO | GO:0000166 Molecular Function | nucleotide binding | 192 / 314 | 61.2% | 70.1% of 274 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 191 / 314 | 60.8% | 69.7% of 274 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Millepora alcicornis | ENSCIQP00000020718.1 | XP_047131452.1 | DNA polymerase epsilon catalytic subunit A [Hydra vulgaris] | Q9WVF7 DNA polymerase epsilon catalytic subunit A OS=Mus musculus O | JBrowse |
| Millepora alcicornis | ENSCIQP00000020895.1 | XP_047131452.1 | DNA polymerase epsilon catalytic subunit A [Hydra vulgaris] | Q9WVF7 DNA polymerase epsilon catalytic subunit A OS=Mus musculus O | JBrowse |
| Millepora alcicornis | ENSCIQP00000020910.1 | XP_047131452.1 | DNA polymerase epsilon catalytic subunit A [Hydra vulgaris] | Q9WVF7 DNA polymerase epsilon catalytic subunit A OS=Mus musculus O | JBrowse |
