Gene Family

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🧬 OG0003080

This orthogroup contains 308 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 78.6%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 308 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR10663GUANYL-NUCLEOTIDE EXCHANGE FACTOR242 / 30878.6%94.5%
of 256
≥50% support
PfamPF01369Sec7246 / 30879.9%93.2%
of 264
≥50% support
PfamPF15410PH_9 — Pleckstrin homology domain244 / 30879.2%92.4%
of 264
≥50% support
PfamPF00595PDZ177 / 30857.5%67.1%
of 264
≥50% support
GOGO:0005085
Molecular Function
guanyl-nucleotide exchange factor activity246 / 30879.9%93.9%
of 262
≥50% support
GOGO:0032012
Biological Process
regulation of ARF protein signal transduction246 / 30879.9%93.9%
of 262
≥50% support
GOGO:0005515
Molecular Function
protein binding245 / 30879.6%93.5%
of 262
≥50% support
GOGO:0005543
Molecular Function
phospholipid binding185 / 30860.1%70.6%
of 262
≥50% support
📊 Total members in OG0003080: 2 (filtered to MALCI · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Millepora alcicornisENSCIQP00000007152.1XP_047128258.1PH and SEC7 domain-containing protein 4 [Hydra vulgaris]Q9NYI0
PH and SEC7 domain-containing protein 3 OS=Homo sapiens OX=9
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Millepora alcicornisENSCIQP00000007159.1XP_047128258.1PH and SEC7 domain-containing protein 4 [Hydra vulgaris]Q2PFD7
PH and SEC7 domain-containing protein 3 OS=Mus musculus OX=1
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