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This orthogroup contains 298 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 298 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | 208 / 298 | 69.8% | 95.9% of 217 | ≥50% support |
| Pfam | PF00488 | MutS_V — MutS domain V | 187 / 298 | 62.8% | 82.7% of 226 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 226 / 298 | 75.8% | 99.1% of 228 | ≥50% support |
| GO | GO:0006298 Biological Process | mismatch repair | 224 / 298 | 75.2% | 98.3% of 228 | ≥50% support |
| GO | GO:0030983 Molecular Function | mismatched DNA binding | 224 / 298 | 75.2% | 98.3% of 228 | ≥50% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 208 / 298 | 69.8% | 91.2% of 228 | ≥50% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 208 / 298 | 69.8% | 91.2% of 228 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 203 / 298 | 68.1% | 89.0% of 228 | ≥50% support |
| GO | GO:0007131 Biological Process | reciprocal meiotic recombination | 201 / 298 | 67.5% | 88.2% of 228 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Millepora alcicornis | ENSCIQP00000015060.1 | XP_047134376.1 | mutS protein homolog 4 isoform X4 [Hydra vulgaris] | O15457 MutS protein homolog 4 OS=Homo sapiens OX=9606 GN=MSH4 PE=1 | JBrowse |
| Millepora alcicornis | ENSCIQP00000015067.1 | XP_047134376.1 | mutS protein homolog 4 isoform X4 [Hydra vulgaris] | O15457 MutS protein homolog 4 OS=Homo sapiens OX=9606 GN=MSH4 PE=1 | JBrowse |
