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This orthogroup contains 258 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 258 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10949 | LIPOYL SYNTHASE | 230 / 258 | 89.2% | 98.3% of 234 | ≥80% support |
| Pfam | PF04055 | Radical_SAM — Radical SAM superfamily | 223 / 258 | 86.4% | 97.8% of 228 | ≥80% support |
| GO | GO:0009107 Biological Process | lipoate biosynthetic process | 232 / 258 | 89.9% | 99.2% of 234 | ≥80% support |
| GO | GO:0016992 Molecular Function | lipoate synthase activity | 232 / 258 | 89.9% | 99.2% of 234 | ≥80% support |
| GO | GO:0051539 Molecular Function | 4 iron, 4 sulfur cluster binding | 232 / 258 | 89.9% | 99.2% of 234 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 230 / 258 | 89.2% | 98.3% of 234 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 229 / 258 | 88.8% | 97.9% of 234 | ≥80% support |
| GO | GO:0051536 Molecular Function | iron-sulfur cluster binding | 229 / 258 | 88.8% | 97.9% of 234 | ≥80% support |
| Pfam | PF16881 | LIAS_N — N-terminal domain of lipoyl synthase of Radical_SAM family | 178 / 258 | 69.0% | 78.1% of 228 | ≥50% support |
| KEGG | K03644 | lipA, LIAS, LIP1, LIP5 — Lipoic acid metabolism | 196 / 258 | 76.0% | 98.5% of 199 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Millepora alcicornis | ENSCIQP00000005404.1 | XP_012559660.1 | lipoyl synthase, mitochondrial-like [Hydra vulgaris] | C3Y3G4 Lipoyl synthase, mitochondrial OS=Branchiostoma floridae OX= | JBrowse |
