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This orthogroup contains 431 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 431 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 265 / 431 | 61.5% | 76.6% of 346 | ≥50% support |
| Pfam | PF00617 | RasGEF | 265 / 431 | 61.5% | 73.0% of 363 | ≥50% support |
| Pfam | PF00618 | RasGEF_N — RasGEF N-terminal motif | 252 / 431 | 58.5% | 69.4% of 363 | ≥50% support |
| Pfam | PF00621 | RhoGEF | 232 / 431 | 53.8% | 63.9% of 363 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 322 / 431 | 74.7% | 92.0% of 350 | ≥50% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 269 / 431 | 62.4% | 76.9% of 350 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 255 / 431 | 59.2% | 72.9% of 350 | ≥50% support |
| GO | GO:0007265 Biological Process | Ras protein signal transduction | 255 / 431 | 59.2% | 72.9% of 350 | ≥50% support |
| GO | GO:0043547 Biological Process | positive regulation of GTPase activity | 255 / 431 | 59.2% | 72.9% of 350 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora capitata | g736.t1 | XP_015773965.1 | PREDICTED: ras-specific guanine nucleotide-releasing factor 2-like isoform X1 [Acropora digitifera] | Q13972 Ras-specific guanine nucleotide-releasing factor 1 OS=Homo s | JBrowse |
