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This orthogroup contains 338 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 338 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24135 | SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN | 286 / 338 | 84.6% | 99.7% of 287 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 283 / 338 | 83.7% | 97.9% of 289 | ≥80% support |
| GO | GO:0030160 Molecular Function | synaptic receptor adaptor activity | 282 / 338 | 83.4% | 97.6% of 289 | ≥80% support |
| GO | GO:0035255 Molecular Function | ionotropic glutamate receptor binding | 282 / 338 | 83.4% | 97.6% of 289 | ≥80% support |
| Pfam | PF12796 | Ank_2 — Ankyrin repeats (3 copies) | 237 / 338 | 70.1% | 84.0% of 282 | ≥50% support |
| Pfam | PF00536 | SAM_1 — SAM domain (Sterile alpha motif) | 234 / 338 | 69.2% | 83.0% of 282 | ≥50% support |
| Pfam | PF00595 | PDZ | 234 / 338 | 69.2% | 83.0% of 282 | ≥50% support |
| Pfam | PF07653 | SH3_2 — Variant SH3 domain | 233 / 338 | 68.9% | 82.6% of 282 | ≥50% support |
| GO | GO:0014069 Cellular Component | postsynaptic density | 247 / 338 | 73.1% | 85.5% of 289 | ≥50% support |
| GO | GO:0043197 Cellular Component | dendritic spine | 247 / 338 | 73.1% | 85.5% of 289 | ≥50% support |
| GO | GO:0045211 Cellular Component | postsynaptic membrane | 247 / 338 | 73.1% | 85.5% of 289 | ≥50% support |
| GO | GO:0051705 Biological Process | obsolete multi-organism behavior | 247 / 338 | 73.1% | 85.5% of 289 | ≥50% support |
| KEGG | K15009 | SHANK — Glutamatergic synapse | 206 / 338 | 61.0% | 99.5% of 207 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora capitata | g14350.t1 | XP_044173350.1 | LOW QUALITY PROTEIN: mucin-5AC-like [Acropora millepora] | Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 OS=Homo sa | JBrowse |
