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This orthogroup contains 318 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 318 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10131 | TNF RECEPTOR ASSOCIATED FACTOR | 286 / 318 | 89.9% | 99.7% of 287 | ≥80% support |
| Pfam | PF21355 | TRAF-mep_MATH — TRAF/meprin, MATH domain | 270 / 318 | 84.9% | 92.2% of 293 | ≥80% support |
| Pfam | PF02176 | zf-TRAF — TRAF-type zinc finger | 268 / 318 | 84.3% | 91.5% of 293 | ≥80% support |
| GO | GO:0033209 Biological Process | tumor necrosis factor-mediated signaling pathway | 286 / 318 | 89.9% | 98.0% of 292 | ≥80% support |
| GO | GO:0070534 Biological Process | protein K63-linked ubiquitination | 286 / 318 | 89.9% | 98.0% of 292 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 272 / 318 | 85.5% | 93.2% of 292 | ≥80% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 270 / 318 | 84.9% | 92.5% of 292 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 195 / 318 | 61.3% | 66.8% of 292 | ≥50% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 195 / 318 | 61.3% | 66.8% of 292 | ≥50% support |
| KEGG | K09848 | TRAF4 — Small cell lung cancer | 213 / 318 | 67.0% | 99.1% of 215 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora capitata | g19186.t1 | none | – | JBrowse |
