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This orthogroup contains 292 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 292 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45670 | E3 UBIQUITIN-PROTEIN LIGASE TRIP12 | 249 / 292 | 85.3% | 100.0% of 249 | ≥80% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 249 / 292 | 85.3% | 99.2% of 251 | ≥80% support |
| GO | GO:0006511 Biological Process | ubiquitin-dependent protein catabolic process | 249 / 292 | 85.3% | 99.2% of 251 | ≥80% support |
| GO | GO:0043161 Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | 249 / 292 | 85.3% | 99.2% of 251 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 249 / 292 | 85.3% | 99.2% of 251 | ≥80% support |
| GO | GO:0016607 Cellular Component | nuclear speck | 245 / 292 | 83.9% | 97.6% of 251 | ≥80% support |
| Pfam | PF00632 | HECT | 210 / 292 | 71.9% | 90.9% of 231 | ≥50% support |
| Pfam | PF02825 | WWE | 192 / 292 | 65.8% | 83.1% of 231 | ≥50% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 216 / 292 | 74.0% | 86.1% of 251 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 191 / 292 | 65.4% | 76.1% of 251 | ≥50% support |
| KEGG | K10590 | TRIP12 — Ubiquitin system | 180 / 292 | 61.6% | 98.4% of 183 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora capitata | g27562.t1 | XP_020611050.1 | E3 ubiquitin-protein ligase TRIP12-like isoform X1 [Orbicella faveolata] | B4F6W9 E3 ubiquitin-protein ligase TRIP12 OS=Xenopus tropicalis OX= | JBrowse |
| Montipora capitata | g27563.t1 | XP_029186235.2 | E3 ubiquitin-protein ligase TRIP12-like [Acropora millepora] | B4F6W9 E3 ubiquitin-protein ligase TRIP12 OS=Xenopus tropicalis OX= | JBrowse |
