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This orthogroup contains 280 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 280 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24006 | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE | 197 / 280 | 70.4% | 93.4% of 211 | ≥50% support |
| Pfam | PF00443 | UCH — Ubiquitin carboxyl-terminal hydrolase | 202 / 280 | 72.1% | 86.7% of 233 | ≥50% support |
| Pfam | PF12436 | USP7_ICP0_bdg — ICP0-binding domain of Ubiquitin-specific protease 7 | 185 / 280 | 66.1% | 79.4% of 233 | ≥50% support |
| Pfam | PF00917 | MATH | 179 / 280 | 63.9% | 76.8% of 233 | ≥50% support |
| Pfam | PF14533 | USP7_C2 — Ubiquitin-specific protease C-terminal | 178 / 280 | 63.6% | 76.4% of 233 | ≥50% support |
| GO | GO:0004843 Molecular Function | cysteine-type deubiquitinase activity | 203 / 280 | 72.5% | 92.3% of 220 | ≥50% support |
| GO | GO:0016579 Biological Process | protein deubiquitination | 203 / 280 | 72.5% | 92.3% of 220 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 197 / 280 | 70.4% | 89.6% of 220 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 197 / 280 | 70.4% | 89.6% of 220 | ≥50% support |
| GO | GO:0031647 Biological Process | regulation of protein stability | 197 / 280 | 70.4% | 89.6% of 220 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 191 / 280 | 68.2% | 86.8% of 220 | ≥50% support |
| KEGG | K11838 | USP7, UBP15 — Ubiquitin system | 171 / 280 | 61.1% | 98.3% of 174 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora capitata | g15829.t1 | XP_029210022.2 | LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 7-like [Acropora millepora] | Q93009 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9 | JBrowse |
