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This orthogroup contains 237 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 237 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13589 | CREB-REGULATED TRANSCRIPTION COACTIVATOR | 201 / 237 | 84.8% | 100.0% of 201 | ≥80% support |
| GO | GO:0008140 Molecular Function | cAMP response element binding protein binding | 204 / 237 | 86.1% | 100.0% of 204 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 201 / 237 | 84.8% | 98.5% of 204 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 201 / 237 | 84.8% | 98.5% of 204 | ≥80% support |
| GO | GO:0032793 Biological Process | positive regulation of CREB transcription factor activity | 201 / 237 | 84.8% | 98.5% of 204 | ≥80% support |
| GO | GO:0045944 Biological Process | positive regulation of transcription by RNA polymerase II | 201 / 237 | 84.8% | 98.5% of 204 | ≥80% support |
| Pfam | PF12886 | TORC_C — Transducer of regulated CREB activity, C terminus | 158 / 237 | 66.7% | 74.5% of 212 | ≥50% support |
| Pfam | PF12885 | TORC_M — Transducer of regulated CREB activity middle domain | 146 / 237 | 61.6% | 68.9% of 212 | ≥50% support |
| Pfam | PF12884 | TORC_N — Transducer of regulated CREB activity, N terminus | 145 / 237 | 61.2% | 68.4% of 212 | ≥50% support |
| GO | GO:0051289 Biological Process | protein homotetramerization | 145 / 237 | 61.2% | 71.1% of 204 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora capitata | g6835.t1 | XP_029179541.1 | CREB-regulated transcription coactivator 1-like isoform X2 [Acropora millepora] | Q3U182 CREB-regulated transcription coactivator 2 OS=Mus musculus O | JBrowse |
