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This orthogroup contains 232 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 232 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10872 | SH2B ADAPTER PROTEIN | 202 / 232 | 87.1% | 100.0% of 202 | ≥80% support |
| GO | GO:0005068 Molecular Function | transmembrane receptor protein tyrosine kinase adaptor activity | 202 / 232 | 87.1% | 100.0% of 202 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 202 / 232 | 87.1% | 100.0% of 202 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 202 / 232 | 87.1% | 100.0% of 202 | ≥80% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 202 / 232 | 87.1% | 100.0% of 202 | ≥80% support |
| GO | GO:0035591 Molecular Function | signaling adaptor activity | 202 / 232 | 87.1% | 100.0% of 202 | ≥80% support |
| Pfam | PF00017 | SH2 | 166 / 232 | 71.6% | 86.0% of 193 | ≥50% support |
| Pfam | PF08916 | Phe_ZIP — Phenylalanine zipper | 150 / 232 | 64.7% | 77.7% of 193 | ≥50% support |
| Pfam | PF00169 | PH | 117 / 232 | 50.4% | 60.6% of 193 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora capricornis | XP_068748252.1 | XP_029188708.2 | LOW QUALITY PROTEIN: SH2B adapter protein 2-like [Acropora millepora] | Q9JID9 SH2B adapter protein 2 OS=Mus musculus OX=10090 GN=Sh2b2 PE= | JBrowse |
