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🧬 OG0004173

This orthogroup contains 265 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 65.3%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 265 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR22845APOPTOTIC PROTEASE-ACTIVATING FACTOR 1173 / 26565.3%75.2%
of 230
≥50% support
PfamPF00400WD40 — WD domain, G-beta repeat202 / 26576.2%87.1%
of 232
≥50% support
PfamPF00619CARD — Caspase recruitment domain183 / 26569.1%78.9%
of 232
≥50% support
PfamPF17908APAF1_C — APAF-1 helical domain182 / 26568.7%78.5%
of 232
≥50% support
PfamPF21296APAF-1-like_WHD — Apoptotic protease-activating factor 1-like, winged-helix domain182 / 26568.7%78.5%
of 232
≥50% support
PfamPF00931NB-ARC181 / 26568.3%78.0%
of 232
≥50% support
GOGO:0005515
Molecular Function
protein binding208 / 26578.5%90.8%
of 229
≥50% support
GOGO:0042981
Biological Process
regulation of apoptotic process183 / 26569.1%79.9%
of 229
≥50% support
GOGO:0043531
Molecular Function
ADP binding181 / 26568.3%79.0%
of 229
≥50% support
KEGGK02084APAF1 — Platinum drug resistance146 / 26555.1%94.8%
of 154
≥50% support
📊 Total members in OG0004173: 3 (filtered to MEFFL · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Montipora efflorescensENSTIFP00000029640.1CAH3017349.1unnamed protein product [Porites evermanni]JBrowse
Montipora efflorescensENSTIFP00000037229.1XP_029185121.2apoptotic protease-activating factor 1 [Acropora millepora]O14727
Apoptotic protease-activating factor 1 OS=Homo sapiens OX=96
JBrowse
Montipora efflorescensENSTIFP00000037234.1CAH3017349.1unnamed protein product [Porites evermanni]O14727
Apoptotic protease-activating factor 1 OS=Homo sapiens OX=96
JBrowse
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