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This orthogroup contains 392 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 392 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13723 | ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE | 303 / 392 | 77.3% | 89.9% of 337 | ≥50% support |
| Pfam | PF00629 | MAM | 305 / 392 | 77.8% | 87.6% of 348 | ≥50% support |
| Pfam | PF17771 | ADAMTS_CR_2 — ADAMTS cysteine-rich domain 2 | 289 / 392 | 73.7% | 83.1% of 348 | ≥50% support |
| Pfam | PF00090 | TSP_1 — Thrombospondin type 1 domain | 270 / 392 | 68.9% | 77.6% of 348 | ≥50% support |
| Pfam | PF19030 | TSP1_ADAMTS — Thrombospondin type 1 domain | 235 / 392 | 60.0% | 67.5% of 348 | ≥50% support |
| Pfam | PF01421 | Reprolysin | 227 / 392 | 57.9% | 65.2% of 348 | ≥50% support |
| Pfam | PF19236 | ADAMTS_CR_3 — ADAMTS cysteine-rich domain | 217 / 392 | 55.4% | 62.4% of 348 | ≥50% support |
| Pfam | PF05986 | ADAMTS_spacer1 — ADAM-TS Spacer 1 | 197 / 392 | 50.3% | 56.6% of 348 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 312 / 392 | 79.6% | 93.1% of 335 | ≥50% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 309 / 392 | 78.8% | 92.2% of 335 | ≥50% support |
| GO | GO:0006508 Biological Process | proteolysis | 309 / 392 | 78.8% | 92.2% of 335 | ≥50% support |
| GO | GO:0030198 Biological Process | extracellular matrix organization | 305 / 392 | 77.8% | 91.0% of 335 | ≥50% support |
| GO | GO:0031012 Cellular Component | extracellular matrix | 302 / 392 | 77.0% | 90.2% of 335 | ≥50% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 296 / 392 | 75.5% | 88.4% of 335 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Micromussa lordhowensis | ENSSYXP00000025213.1 | XP_020629328.1 | A disintegrin and metalloproteinase with thrombospondin motifs 3-like [Orbicella faveolata] | Q8WXS8 A disintegrin and metalloproteinase with thrombospondin moti | JBrowse |
| Micromussa lordhowensis | ENSSYXP00000025238.1 | XP_020629328.1 | A disintegrin and metalloproteinase with thrombospondin motifs 3-like [Orbicella faveolata] | Q8TE56 A disintegrin and metalloproteinase with thrombospondin moti | JBrowse |
