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This orthogroup contains 262 genes from 135 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 262 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10110 | SODIUM/HYDROGEN EXCHANGER | 163 / 262 | 62.2% | 81.9% of 199 | ≥50% support |
| Pfam | PF00999 | Na_H_Exchanger — Sodium/hydrogen exchanger family | 170 / 262 | 64.9% | 81.0% of 210 | ≥50% support |
| Pfam | PF00520 | Ion_trans — Ion transport protein | 156 / 262 | 59.5% | 74.3% of 210 | ≥50% support |
| Pfam | PF00027 | cNMP_binding — Cyclic nucleotide-binding domain | 154 / 262 | 58.8% | 73.3% of 210 | ≥50% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 192 / 262 | 73.3% | 97.5% of 197 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 192 / 262 | 73.3% | 97.5% of 197 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 188 / 262 | 71.8% | 95.4% of 197 | ≥50% support |
| GO | GO:1902600 Biological Process | proton transmembrane transport | 170 / 262 | 64.9% | 86.3% of 197 | ≥50% support |
| GO | GO:0015297 Molecular Function | antiporter activity | 170 / 262 | 64.9% | 86.3% of 197 | ≥50% support |
| GO | GO:0006812 Biological Process | monoatomic cation transport | 170 / 262 | 64.9% | 86.3% of 197 | ≥50% support |
| GO | GO:0015386 Molecular Function | potassium:proton antiporter activity | 163 / 262 | 62.2% | 82.7% of 197 | ≥50% support |
| GO | GO:0051453 Biological Process | regulation of intracellular pH | 163 / 262 | 62.2% | 82.7% of 197 | ≥50% support |
| GO | GO:0015385 Molecular Function | sodium:proton antiporter activity | 163 / 262 | 62.2% | 82.7% of 197 | ≥50% support |
| GO | GO:0071805 Biological Process | potassium ion transmembrane transport | 163 / 262 | 62.2% | 82.7% of 197 | ≥50% support |
| GO | GO:0098719 Biological Process | sodium ion import across plasma membrane | 163 / 262 | 62.2% | 82.7% of 197 | ≥50% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 156 / 262 | 59.5% | 79.2% of 197 | ≥50% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 156 / 262 | 59.5% | 79.2% of 197 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Micromussa lordhowensis | ENSSYXP00000037132.1 | CAH3106667.1 | unnamed protein product [Pocillopora meandrina] | A3RL54 Sperm-specific sodium:proton exchanger OS=Strongylocentrotus | JBrowse |
