Gene Family

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🧬 OG0000177

This orthogroup contains 2,956 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 56.9%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 2,956 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR24416TYROSINE-PROTEIN KINASE RECEPTOR1682 / 2,95656.9%64.6%
of 2,603
≥50% support
PfamPF07714PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase1711 / 2,95657.9%64.1%
of 2,671
≥50% support
PfamPF07679I-set1572 / 2,95653.2%58.9%
of 2,671
≥50% support
GOGO:0005524
Molecular Function
ATP binding1737 / 2,95658.8%80.7%
of 2,153
≥50% support
GOGO:0006468
Biological Process
protein phosphorylation1717 / 2,95658.1%79.8%
of 2,153
≥50% support
GOGO:0004672
Molecular Function
protein kinase activity1716 / 2,95658.1%79.7%
of 2,153
≥50% support
GOGO:0005887
Cellular Component
plasma membrane1683 / 2,95656.9%78.2%
of 2,153
≥50% support
GOGO:0007275
Biological Process
multicellular organism development1679 / 2,95656.8%78.0%
of 2,153
≥50% support
GOGO:0007169
Biological Process
cell surface receptor protein tyrosine kinase signaling pathway1670 / 2,95656.5%77.6%
of 2,153
≥50% support
GOGO:0004714
Molecular Function
transmembrane receptor protein tyrosine kinase activity1669 / 2,95656.5%77.5%
of 2,153
≥50% support
GOGO:0043235
Cellular Component
receptor complex1669 / 2,95656.5%77.5%
of 2,153
≥50% support
GOGO:0033674
Biological Process
positive regulation of kinase activity1668 / 2,95656.4%77.5%
of 2,153
≥50% support
GOGO:0004713
Molecular Function
protein tyrosine kinase activity1540 / 2,95652.1%71.5%
of 2,153
≥50% support
📊 Total members in OG0000177: 18 (filtered to MMURI · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Muricea muricataBRAKERXEIP00000001403.1XP_028390734.1uncharacterized protein LOC114515639 isoform X2 [Dendronephthya gigantea]P35546
Proto-oncogene tyrosine-protein kinase receptor Ret OS=Mus m
JBrowse
Muricea muricataBRAKERXEIP00000009184.1CAB3993442.1Fibroblast growth factor receptor 1 [Paramuricea clavata]G3V9H8
Proto-oncogene tyrosine-protein kinase receptor Ret OS=Rattu
JBrowse
Muricea muricataBRAKERXEIP00000011029.1CAB3993442.1Fibroblast growth factor receptor 1 [Paramuricea clavata]P35590
Tyrosine-protein kinase receptor Tie-1 OS=Homo sapiens OX=96
JBrowse
Muricea muricataBRAKERXEIP00000024062.1CAB3993442.1Fibroblast growth factor receptor 1 [Paramuricea clavata]Q91287
Fibroblast growth factor receptor 3 OS=Pleurodeles waltl OX=
JBrowse
Muricea muricataBRAKERXEIP00000024610.1CAB3993442.1Fibroblast growth factor receptor 1 [Paramuricea clavata]G3V9H8
Proto-oncogene tyrosine-protein kinase receptor Ret OS=Rattu
JBrowse
Muricea muricataBRAKERXEIP00000024633.1CAB3993442.1Fibroblast growth factor receptor 1 [Paramuricea clavata]G3V9H8
Proto-oncogene tyrosine-protein kinase receptor Ret OS=Rattu
JBrowse
Muricea muricataBRAKERXEIP00000024782.1CAB3993442.1Fibroblast growth factor receptor 1 [Paramuricea clavata]P07949
Proto-oncogene tyrosine-protein kinase receptor Ret OS=Homo
JBrowse
Muricea muricataBRAKERXEIP00000024814.1CAB3993442.1Fibroblast growth factor receptor 1 [Paramuricea clavata]G3V9H8
Proto-oncogene tyrosine-protein kinase receptor Ret OS=Rattu
JBrowse
Muricea muricataBRAKERXEIP00000047062.1CAB4011993.1fibroblast growth factor receptor 4-like [Paramuricea clavata]JBrowse
Muricea muricataBRAKERXEIP00000047162.1CAB3989129.1fibroblast growth factor receptor homolog 1-like isoform X2 [Paramuricea clavata]P22607
Fibroblast growth factor receptor 3 OS=Homo sapiens OX=9606
JBrowse
Muricea muricataBRAKERXEIP00000047468.1CAB4011993.1fibroblast growth factor receptor 4-like [Paramuricea clavata]P18460
Fibroblast growth factor receptor 3 OS=Gallus gallus OX=9031
JBrowse
Muricea muricataBRAKERXEIP00000047725.1CAB3994735.1fibroblast growth factor receptor 2-like isoform X1 [Paramuricea clavata]Q03364
Fibroblast growth factor receptor 2 OS=Xenopus laevis OX=835
JBrowse
Muricea muricataBRAKERXEIP00000047743.1CAB3994734.1fibroblast growth factor receptor 2-like isoform X1 [Paramuricea clavata]P18460
Fibroblast growth factor receptor 3 OS=Gallus gallus OX=9031
JBrowse
Muricea muricataBRAKERXEIP00000047995.1CAB4011993.1fibroblast growth factor receptor 4-like [Paramuricea clavata]Q91288
Fibroblast growth factor receptor 4 OS=Pleurodeles waltl OX=
JBrowse
Muricea muricataBRAKERXEIP00000048338.1CAB3999207.1fibroblast growth factor receptor 2-like isoform X1 [Paramuricea clavata]Q8NDA2
Hemicentin-2 OS=Homo sapiens OX=9606 GN=HMCN2 PE=1 SV=4
JBrowse
Muricea muricataBRAKERXEIP00000048522.1CAB3977038.1fibroblast growth factor receptor 4-like, partial [Paramuricea clavata]P22607
Fibroblast growth factor receptor 3 OS=Homo sapiens OX=9606
JBrowse
Muricea muricataBRAKERXEIP00000048537.1CAB4001687.1fibroblast growth factor receptor 2-like isoform X1, partial [Paramuricea clavata]Q7T2H2
Fibroblast growth factor receptor-like 1 OS=Gallus gallus OX
JBrowse
Muricea muricataBRAKERXEIP00000048686.1XP_028403296.1fibroblast growth factor receptor 4-like isoform X1 [Dendronephthya gigantea]P16170
Neural cell adhesion molecule 1-A OS=Xenopus laevis OX=8355
JBrowse
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