Gene Family

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Member genes
2,575
Species
145
Sequences
2,575
Best annotation support
90.7%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.7% of the 2,575 members.

Support counts the member genes carrying the term. % of genes is that count over all 2,575 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00010HLH — Helix-loop-helix DNA-binding domain2335 / 2,57590.7%99.9%
of 2,337
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity2337 / 2,57590.8%100.0%
of 2,338
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific2321 / 2,57590.1%99.3%
of 2,338
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II2156 / 2,57583.7%92.2%
of 2,338
≥80% support
PANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1851 / 2,57571.9%79.7%
of 2,324
≥50% support
GOGO:0000977
Molecular Function
RNA polymerase II transcription regulatory region sequence-specific DNA binding1851 / 2,57571.9%79.2%
of 2,338
≥50% support
GOGO:0032502
Biological Process
developmental process1851 / 2,57571.9%79.2%
of 2,338
≥50% support
📊 Total members in OG0000221: 16 (filtered to MMURI · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Muricea muricataBRAKERXEIP00000022327.1CAB4015430.1class A basic helix-loop-helix 15 [Paramuricea clavata]Q9Y0A7
Basic helix-loop-helix transcription factor amos OS=Drosophi
JBrowse
Muricea muricataBRAKERXEIP00000032114.1CAB3980624.1T-cell acute lymphocytic leukemia 1 homolog [Paramuricea clavata]O93507
T-cell acute lymphocytic leukemia protein 1 homolog OS=Danio
JBrowse
Muricea muricataBRAKERXEIP00000032190.1XP_028411579.1pancreas transcription factor 1 subunit alpha-like [Dendronephthya gigantea]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
Muricea muricataBRAKERXEIP00000036768.1CAB3987095.1twist-related 2-like [Paramuricea clavata]P13903
Twist-related protein OS=Xenopus laevis OX=8355 GN=twist1 PE
JBrowse
Muricea muricataBRAKERXEIP00000036935.1XP_028411579.1pancreas transcription factor 1 subunit alpha-like [Dendronephthya gigantea]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
Muricea muricataBRAKERXEIP00000037850.1CAB3981887.1transcription factor 15-like [Paramuricea clavata]P13903
Twist-related protein OS=Xenopus laevis OX=8355 GN=twist1 PE
JBrowse
Muricea muricataBRAKERXEIP00000038117.1CAB3981292.1basic helix-loop-helix transcription factor scleraxis-like [Paramuricea clavata]JBrowse
Muricea muricataBRAKERXEIP00000038243.1CAB4000062.1transcription factor 15-like [Paramuricea clavata]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Muricea muricataBRAKERXEIP00000041072.1CAB3991039.1heart- and neural crest derivatives-expressed protein 1 [Paramuricea clavata]Q90690
Heart- and neural crest derivatives-expressed protein 2 OS=G
JBrowse
Muricea muricataBRAKERXEIP00000042200.1CAB3998897.1neurogenic differentiation factor 1 [Paramuricea clavata]JBrowse
Muricea muricataBRAKERXEIP00000042760.1CAB3981242.1Hand-RA [Paramuricea clavata]Q90691
Heart- and neural crest derivatives-expressed protein 1 OS=G
JBrowse
Muricea muricataBRAKERXEIP00000044826.1CAB4030725.1dhand, partial, partial [Paramuricea clavata]P57102
Heart- and neural crest derivatives-expressed protein 2 OS=D
JBrowse
Muricea muricataBRAKERXEIP00000049268.1CAB4001068.1achaete-scute homolog 2 [Paramuricea clavata]Q2EGB9
Achaete-scute homolog 2 OS=Bos taurus OX=9913 GN=ASCL2 PE=2
JBrowse
Muricea muricataBRAKERXEIP00000049444.1CAB4006605.1achaete-scute homolog 4-like [Paramuricea clavata]M0QWB7
Achaete-scute homolog 5 OS=Mus musculus OX=10090 GN=Ascl5 PE
JBrowse
Muricea muricataBRAKERXEIP00000049723.1CAB4035986.1achaete-scute homolog 1, partial [Paramuricea clavata]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Muricea muricataBRAKERXEIP00000049782.1CAB3977675.1achaete-scute homolog 1-like [Paramuricea clavata]JBrowse
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