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This orthogroup contains 469 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 469 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12127 | MUCOLIPIN | 406 / 469 | 86.6% | 99.8% of 407 | ≥80% support |
| GO | GO:0005261 Molecular Function | monoatomic cation channel activity | 406 / 469 | 86.6% | 99.8% of 407 | ≥80% support |
| GO | GO:0005765 Cellular Component | lysosomal membrane | 406 / 469 | 86.6% | 99.8% of 407 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 406 / 469 | 86.6% | 99.8% of 407 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 406 / 469 | 86.6% | 99.8% of 407 | ≥80% support |
| GO | GO:0072345 Molecular Function | NAADP-sensitive calcium-release channel activity | 406 / 469 | 86.6% | 99.8% of 407 | ≥80% support |
| Pfam | PF21381 | MCLN_ECD — Mucolipin, extracytosolic domain | 333 / 469 | 71.0% | 87.6% of 380 | ≥50% support |
| Pfam | PF08016 | PKD_channel — Polycystin cation channel | 279 / 469 | 59.5% | 73.4% of 380 | ≥50% support |
| KEGG | K04994 | MCOLN3, TRPML3 — Ion channels | 281 / 469 | 59.9% | 96.9% of 290 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Muricea muricata | BRAKERXEIP00000035394.1 | XP_028413461.1 | mucolipin-3-like isoform X2 [Dendronephthya gigantea] | Q8R4F0 Mucolipin-3 OS=Mus musculus OX=10090 GN=Mcoln3 PE=1 SV=1 | JBrowse |
