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This orthogroup contains 413 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 413 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11607 | ALPHA-MANNOSIDASE | 364 / 413 | 88.1% | 100.0% of 364 | ≥80% support |
| Pfam | PF01074 | Glyco_hydro_38N — Glycosyl hydrolases family 38 N-terminal domain | 339 / 413 | 82.1% | 93.4% of 363 | ≥80% support |
| GO | GO:0005975 Biological Process | carbohydrate metabolic process | 365 / 413 | 88.4% | 100.0% of 365 | ≥80% support |
| GO | GO:0004559 Molecular Function | alpha-mannosidase activity | 364 / 413 | 88.1% | 99.7% of 365 | ≥80% support |
| GO | GO:0006013 Biological Process | mannose metabolic process | 362 / 413 | 87.7% | 99.2% of 365 | ≥80% support |
| GO | GO:0005764 Cellular Component | lysosome | 359 / 413 | 86.9% | 98.4% of 365 | ≥80% support |
| Pfam | PF07748 | Glyco_hydro_38C — Glycosyl hydrolases family 38 C-terminal domain | 282 / 413 | 68.3% | 77.7% of 363 | ≥50% support |
| Pfam | PF09261 | Alpha-mann_mid — Alpha mannosidase middle domain | 282 / 413 | 68.3% | 77.7% of 363 | ≥50% support |
| Pfam | PF21260 | Laman-like_dom — Lysosomal alpha-mannosidase-like, central domain | 233 / 413 | 56.4% | 64.2% of 363 | ≥50% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 290 / 413 | 70.2% | 79.5% of 365 | ≥50% support |
| GO | GO:0030246 Molecular Function | carbohydrate binding | 290 / 413 | 70.2% | 79.5% of 365 | ≥50% support |
| KEGG | K12311 | MAN2B1, LAMAN — Lysosome | 249 / 413 | 60.3% | 93.6% of 266 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Muricea muricata | BRAKERXEIP00000039818.1 | CAB3995555.1 | Lysosomal alpha-mannosidase [Paramuricea clavata] | Q8VHC8 Lysosomal alpha-mannosidase OS=Cavia porcellus OX=10141 GN=M | JBrowse |
| Muricea muricata | BRAKERXEIP00000052691.1 | CAB4008439.1 | Lysosomal alpha-mannosidase [Paramuricea clavata] | Q60HE9 Lysosomal alpha-mannosidase OS=Macaca fascicularis OX=9541 G | JBrowse |
