OG0002341

View gene tree Interactive tree, one tip per member sequence

Member genes: 366
Species: 144
Sequences: 366
Best annotation support: 89.9%

Downloads ⬇ Alignment (FASTA.gz) ⬇ Sequences (FASTA)

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 89.9% of the 366 members.

Support counts the member genes carrying the term. % of genes is that count over all 366 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source	Term	Name / description	Support	% of genes	% annotated	Consistency
PANTHER	PTHR46276	E3 UBIQUITIN-PROTEIN LIGASE UBR5	329 / 366	89.9%	100.0% of 329	≥80% support
GO	GO:0000209 Biological Process	protein polyubiquitination	329 / 366	89.9%	100.0% of 329	≥80% support
GO	GO:0005634 Cellular Component	nucleus	329 / 366	89.9%	100.0% of 329	≥80% support
GO	GO:0005737 Cellular Component	cytoplasm	329 / 366	89.9%	100.0% of 329	≥80% support
GO	GO:0034450 Molecular Function	ubiquitin-ubiquitin ligase activity	329 / 366	89.9%	100.0% of 329	≥80% support
GO	GO:0090263 Biological Process	positive regulation of canonical Wnt signaling pathway	329 / 366	89.9%	100.0% of 329	≥80% support
Pfam	PF00632	HECT	220 / 366	60.1%	82.4% of 267	≥50% support
Pfam	PF00658	PABP — Poly-adenylate binding protein, unique domain	202 / 366	55.2%	75.7% of 267	≥50% support
GO	GO:0004842 Molecular Function	ubiquitin-protein transferase activity	221 / 366	60.4%	67.2% of 329	≥50% support
GO	GO:0003723 Molecular Function	RNA binding	204 / 366	55.7%	62.0% of 329	≥50% support
GO	GO:0008270 Molecular Function	zinc ion binding	204 / 366	55.7%	62.0% of 329	≥50% support

📊 Total members in OG0002341: 1 (filtered to MMURI · show all species)

Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species	Gene ID	Top NCBI-NR hit (accession)	Top NCBI-NR hit description (source organism)	Top UniProt hit (Swiss-Prot)	Genome browser
Muricea muricata	BRAKERXEIP00000024459.1	CAB3992156.1	E3 ubiquitin- ligase UBR5 isoform X2 [Paramuricea clavata]	Q80TP3 E3 ubiquitin-protein ligase UBR5 OS=Mus musculus OX=10090 GN	JBrowse

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