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This orthogroup contains 318 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 318 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43806 | PEPTIDASE S8 | 204 / 318 | 64.2% | 95.8% of 213 | ≥50% support |
| Pfam | PF12580 | TPPII — Tripeptidyl peptidase II | 212 / 318 | 66.7% | 82.8% of 256 | ≥50% support |
| Pfam | PF00082 | Peptidase_S8 — Subtilase family | 209 / 318 | 65.7% | 81.6% of 256 | ≥50% support |
| Pfam | PF21223 | TPPII_Ig-like-1 — Tripeptidyl-peptidase II, first Ig-like domain | 200 / 318 | 62.9% | 78.1% of 256 | ≥50% support |
| Pfam | PF21316 | TPPII_GBD — TPPII, galactose-binding domain-like | 198 / 318 | 62.3% | 77.3% of 256 | ≥50% support |
| GO | GO:0006508 Biological Process | proteolysis | 230 / 318 | 72.3% | 97.9% of 235 | ≥50% support |
| GO | GO:0004252 Molecular Function | serine-type endopeptidase activity | 229 / 318 | 72.0% | 97.5% of 235 | ≥50% support |
| GO | GO:0008236 Molecular Function | serine-type peptidase activity | 209 / 318 | 65.7% | 88.9% of 235 | ≥50% support |
| GO | GO:0008240 Molecular Function | tripeptidyl-peptidase activity | 205 / 318 | 64.5% | 87.2% of 235 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 204 / 318 | 64.2% | 86.8% of 235 | ≥50% support |
| KEGG | K01280 | TPP2 — Chaperones and folding catalysts | 179 / 318 | 56.3% | 97.3% of 184 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Muricea muricata | BRAKERXEIP00000040799.1 | XP_028405657.1 | tripeptidyl-peptidase 2-like [Dendronephthya gigantea] | P29144 Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 | JBrowse |
