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This orthogroup contains 308 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 308 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13179 | DEP DOMAIN CONTAINING PROTEIN 5 | 261 / 308 | 84.7% | 98.9% of 264 | ≥80% support |
| GO | GO:0005096 Molecular Function | GTPase activator activity | 261 / 308 | 84.7% | 98.5% of 265 | ≥80% support |
| GO | GO:0010508 Biological Process | positive regulation of autophagy | 261 / 308 | 84.7% | 98.5% of 265 | ≥80% support |
| GO | GO:1904262 Biological Process | negative regulation of TORC1 signaling | 261 / 308 | 84.7% | 98.5% of 265 | ≥80% support |
| GO | GO:1990130 Cellular Component | GATOR1 complex | 261 / 308 | 84.7% | 98.5% of 265 | ≥80% support |
| GO | GO:0005765 Cellular Component | lysosomal membrane | 254 / 308 | 82.5% | 95.9% of 265 | ≥80% support |
| GO | GO:0034198 Biological Process | cellular response to amino acid starvation | 254 / 308 | 82.5% | 95.9% of 265 | ≥80% support |
| Pfam | PF19418 | DEPDC5_CTD — DEPDC5 protein C-terminal region | 207 / 308 | 67.2% | 83.8% of 247 | ≥50% support |
| Pfam | PF12257 | IML1 | 196 / 308 | 63.6% | 79.4% of 247 | ≥50% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 184 / 308 | 59.7% | 69.4% of 265 | ≥50% support |
| KEGG | K20404 | DEPDC5, SEA1 — Membrane trafficking | 170 / 308 | 55.2% | 97.1% of 175 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Muricea muricata | BRAKERXEIP00000027134.1 | XP_028415171.1 | GATOR complex protein DEPDC5-like isoform X1 [Dendronephthya gigantea] | P61460 GATOR1 complex protein DEPDC5 OS=Mus musculus OX=10090 GN=De | JBrowse |
| Muricea muricata | BRAKERXEIP00000028073.1 | CAB4009073.1 | DEP domain-containing 5 [Paramuricea clavata] | – | JBrowse |
