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This orthogroup contains 236 genes from 134 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 236 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13295 | GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT | 204 / 236 | 86.4% | 100.0% of 204 | ≥80% support |
| GO | GO:0006750 Biological Process | glutathione biosynthetic process | 204 / 236 | 86.4% | 100.0% of 204 | ≥80% support |
| GO | GO:0017109 Cellular Component | glutamate-cysteine ligase complex | 204 / 236 | 86.4% | 100.0% of 204 | ≥80% support |
| GO | GO:0030234 Molecular Function | enzyme regulator activity | 204 / 236 | 86.4% | 100.0% of 204 | ≥80% support |
| GO | GO:0035226 Molecular Function | glutamate-cysteine ligase catalytic subunit binding | 204 / 236 | 86.4% | 100.0% of 204 | ≥80% support |
| GO | GO:0035229 Biological Process | positive regulation of glutamate-cysteine ligase activity | 204 / 236 | 86.4% | 100.0% of 204 | ≥80% support |
| Pfam | PF00248 | Aldo_ket_red — Aldo/keto reductase family | 147 / 236 | 62.3% | 99.3% of 148 | ≥50% support |
| KEGG | K11205 | GCLM — Ferroptosis | 154 / 236 | 65.3% | 100.0% of 154 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Muricea muricata | BRAKERXEIP00000024840.1 | XP_028395013.1 | glutamate--cysteine ligase regulatory subunit-like [Dendronephthya gigantea] | O09172 Glutamate--cysteine ligase regulatory subunit OS=Mus musculu | JBrowse |
| Muricea muricata | BRAKERXEIP00000025004.1 | XP_028395013.1 | glutamate--cysteine ligase regulatory subunit-like [Dendronephthya gigantea] | O09172 Glutamate--cysteine ligase regulatory subunit OS=Mus musculu | JBrowse |
