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This orthogroup contains 234 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 234 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24171 | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED | 168 / 234 | 71.8% | 84.9% of 198 | ≥50% support |
| Pfam | PF12796 | Ank_2 — Ankyrin repeats (3 copies) | 168 / 234 | 71.8% | 83.6% of 201 | ≥50% support |
| Pfam | PF00533 | BRCT | 159 / 234 | 68.0% | 79.1% of 201 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 184 / 234 | 78.6% | 91.5% of 201 | ≥50% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 182 / 234 | 77.8% | 90.6% of 201 | ≥50% support |
| GO | GO:0031436 Cellular Component | BRCA1-BARD1 complex | 182 / 234 | 77.8% | 90.6% of 201 | ≥50% support |
| GO | GO:0070531 Cellular Component | BRCA1-A complex | 182 / 234 | 77.8% | 90.6% of 201 | ≥50% support |
| GO | GO:0085020 Biological Process | protein K6-linked ubiquitination | 168 / 234 | 71.8% | 83.6% of 201 | ≥50% support |
| KEGG | K10683 | BARD1 — DNA repair and recombination proteins | 144 / 234 | 61.5% | 97.3% of 148 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Muricea muricata | BRAKERXEIP00000031482.1 | CAB3987440.1 | BRCA1-associated RING domain 1-like isoform X2 [Paramuricea clavata] | Q99728 BRCA1-associated RING domain protein 1 OS=Homo sapiens OX=96 | JBrowse |
