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This orthogroup contains 3,705 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,705 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10131 | TNF RECEPTOR ASSOCIATED FACTOR | 3218 / 3,705 | 86.9% | 99.7% of 3,227 | ≥80% support |
| GO | GO:0033209 Biological Process | tumor necrosis factor-mediated signaling pathway | 3100 / 3,705 | 83.7% | 94.4% of 3,283 | ≥80% support |
| GO | GO:0070534 Biological Process | protein K63-linked ubiquitination | 3100 / 3,705 | 83.7% | 94.4% of 3,283 | ≥80% support |
| Pfam | PF21355 | TRAF-mep_MATH — TRAF/meprin, MATH domain | 2732 / 3,705 | 73.7% | 83.7% of 3,264 | ≥50% support |
| Pfam | PF02176 | zf-TRAF — TRAF-type zinc finger | 2490 / 3,705 | 67.2% | 76.3% of 3,264 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 2918 / 3,705 | 78.8% | 88.9% of 3,283 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 2785 / 3,705 | 75.2% | 84.8% of 3,283 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 2406 / 3,705 | 64.9% | 73.3% of 3,283 | ≥50% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 2404 / 3,705 | 64.9% | 73.2% of 3,283 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000016775.1 | XP_022801567.1 | TNF receptor-associated factor 3-like [Stylophora pistillata] | P70191 TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN | JBrowse |
| Mastigias papua | BRAKERKYLP00000018076.1 | CAH3189132.1 | unnamed protein product [Porites evermanni] | – | JBrowse |
| Mastigias papua | BRAKERKYLP00000022642.1 | XP_020613324.1 | TNF receptor-associated factor 3-like [Orbicella faveolata] | Q12933 TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN= | JBrowse |
| Mastigias papua | BRAKERKYLP00000023144.1 | XP_020613324.1 | TNF receptor-associated factor 3-like [Orbicella faveolata] | Q60803 TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN | JBrowse |
| Mastigias papua | BRAKERKYLP00000023990.1 | KAJ7365566.1 | TNF receptor-associated factor 3 [Desmophyllum pertusum] | Q60803 TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN | JBrowse |
| Mastigias papua | BRAKERKYLP00000024490.1 | KAG7238056.1 | hypothetical protein INR49_031410 [Caranx melampygus] | Q60803 TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN | JBrowse |
