Gene Family

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Member genes
2,575
Species
145
Sequences
2,575
Best annotation support
90.7%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.7% of the 2,575 members.

Support counts the member genes carrying the term. % of genes is that count over all 2,575 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00010HLH — Helix-loop-helix DNA-binding domain2335 / 2,57590.7%99.9%
of 2,337
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity2337 / 2,57590.8%100.0%
of 2,338
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific2321 / 2,57590.1%99.3%
of 2,338
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II2156 / 2,57583.7%92.2%
of 2,338
≥80% support
PANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1851 / 2,57571.9%79.7%
of 2,324
≥50% support
GOGO:0000977
Molecular Function
RNA polymerase II transcription regulatory region sequence-specific DNA binding1851 / 2,57571.9%79.2%
of 2,338
≥50% support
GOGO:0032502
Biological Process
developmental process1851 / 2,57571.9%79.2%
of 2,338
≥50% support
📊 Total members in OG0000221: 16 (filtered to MPAPU · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Mastigias papuaBRAKERKYLP00000000238.1XP_032657102.1helix-loop-helix protein 2-like [Chelonoidis abingdonii]Q02577
Helix-loop-helix protein 2 OS=Homo sapiens OX=9606 GN=NHLH2
JBrowse
Mastigias papuaBRAKERKYLP00000000295.1XP_001628329.2transcription factor atoh8 [Nematostella vectensis]D2CLZ9
Transcription factor atoh8 OS=Danio rerio OX=7955 GN=atoh8 P
JBrowse
Mastigias papuaBRAKERKYLP00000000672.1NWZ84268.1HAND1 protein [Poecile atricapillus]Q90691
Heart- and neural crest derivatives-expressed protein 1 OS=G
JBrowse
Mastigias papuaBRAKERKYLP00000004862.1noneJBrowse
Mastigias papuaBRAKERKYLP00000005735.1CEG06182.1transcription factor, partial [Clytia hemisphaerica]Q08DI0
Neurogenic differentiation factor 6 OS=Bos taurus OX=9913 GN
JBrowse
Mastigias papuaBRAKERKYLP00000006633.1AAQ75377.1transcription factor Atl1 [Podocoryna carnea]Q8N100
Transcription factor ATOH7 OS=Homo sapiens OX=9606 GN=ATOH7
JBrowse
Mastigias papuaBRAKERKYLP00000014102.1XP_032241387.2pancreas transcription factor 1 subunit alpha [Nematostella vectensis]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
Mastigias papuaBRAKERKYLP00000014422.1ALJ33557.1Hlh-4 [Clytia hemisphaerica]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
Mastigias papuaBRAKERKYLP00000014716.1CAH3145619.1unnamed protein product [Porites lobata]P13903
Twist-related protein OS=Xenopus laevis OX=8355 GN=twist1 PE
JBrowse
Mastigias papuaBRAKERKYLP00000016428.1XP_012554514.1N-myc protein-like [Hydra vulgaris]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Mastigias papuaBRAKERKYLP00000016552.1AFV31436.1Ash [Hydractinia echinata]Q90260
Achaete-scute homolog 1b OS=Danio rerio OX=7955 GN=ascl1b PE
JBrowse
Mastigias papuaBRAKERKYLP00000016664.1XP_015762589.1PREDICTED: achaete-scute homolog 1a-like [Acropora digitifera]JBrowse
Mastigias papuaBRAKERKYLP00000017049.1AAR04871.1achaete-scute-like protein [Hydra vulgaris]M0QWB7
Achaete-scute homolog 5 OS=Mus musculus OX=10090 GN=Ascl5 PE
JBrowse
Mastigias papuaBRAKERKYLP00000017174.1CEG06176.1bHLH transcription factor Paraxis, partial [Clytia hemisphaerica]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Mastigias papuaBRAKERKYLP00000018631.1EDO46193.1predicted protein, partial [Nematostella vectensis]Q9Y4Z2
Neurogenin-3 OS=Homo sapiens OX=9606 GN=NEUROG3 PE=1 SV=2
JBrowse
Mastigias papuaBRAKERKYLP00000019565.1noneJBrowse
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