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This orthogroup contains 716 genes from 148 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 716 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11977 | VILLIN | 588 / 716 | 82.1% | 99.8% of 589 | ≥80% support |
| GO | GO:0051015 Molecular Function | actin filament binding | 592 / 716 | 82.7% | 99.8% of 593 | ≥80% support |
| GO | GO:0005546 Molecular Function | phosphatidylinositol-4,5-bisphosphate binding | 588 / 716 | 82.1% | 99.2% of 593 | ≥80% support |
| GO | GO:0051014 Biological Process | actin filament severing | 588 / 716 | 82.1% | 99.2% of 593 | ≥80% support |
| GO | GO:0051016 Biological Process | barbed-end actin filament capping | 588 / 716 | 82.1% | 99.2% of 593 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 586 / 716 | 81.8% | 98.8% of 593 | ≥80% support |
| GO | GO:0008154 Biological Process | actin polymerization or depolymerization | 586 / 716 | 81.8% | 98.8% of 593 | ≥80% support |
| GO | GO:0015629 Cellular Component | actin cytoskeleton | 586 / 716 | 81.8% | 98.8% of 593 | ≥80% support |
| Pfam | PF00626 | Gelsolin | 480 / 716 | 67.0% | 85.4% of 562 | ≥50% support |
| Pfam | PF02209 | VHP — Villin headpiece domain | 443 / 716 | 61.9% | 78.8% of 562 | ≥50% support |
| GO | GO:0003779 Molecular Function | actin binding | 472 / 716 | 65.9% | 79.6% of 593 | ≥50% support |
| GO | GO:0007010 Biological Process | cytoskeleton organization | 472 / 716 | 65.9% | 79.6% of 593 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000004547.1 | XP_012567191.2 | supervillin isoform X3 [Hydra vulgaris] | Q8K4L3 Supervillin OS=Mus musculus OX=10090 GN=Svil PE=1 SV=1 | JBrowse |
| Mastigias papua | BRAKERKYLP00000015922.1 | XP_047146068.1 | supervillin [Hydra vulgaris] | O46385 Supervillin OS=Bos taurus OX=9913 GN=SVIL PE=1 SV=2 | JBrowse |
