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This orthogroup contains 586 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 586 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45655 | GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 | 516 / 586 | 88.1% | 99.6% of 518 | ≥80% support |
| Pfam | PF00211 | Guanylate_cyc — Adenylate and Guanylate cyclase catalytic domain | 500 / 586 | 85.3% | 95.8% of 522 | ≥80% support |
| Pfam | PF07701 | HNOBA — Heme NO binding associated | 491 / 586 | 83.8% | 94.1% of 522 | ≥80% support |
| Pfam | PF07700 | HNOB — Haem-NO-binding | 489 / 586 | 83.5% | 93.7% of 522 | ≥80% support |
| GO | GO:0004383 Molecular Function | guanylate cyclase activity | 515 / 586 | 87.9% | 98.7% of 522 | ≥80% support |
| GO | GO:0008074 Cellular Component | guanylate cyclase complex, soluble | 514 / 586 | 87.7% | 98.5% of 522 | ≥80% support |
| GO | GO:0019934 Biological Process | cGMP-mediated signaling | 514 / 586 | 87.7% | 98.5% of 522 | ≥80% support |
| GO | GO:0070482 Biological Process | response to oxygen levels | 514 / 586 | 87.7% | 98.5% of 522 | ≥80% support |
| GO | GO:0009190 Biological Process | cyclic nucleotide biosynthetic process | 500 / 586 | 85.3% | 95.8% of 522 | ≥80% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 500 / 586 | 85.3% | 95.8% of 522 | ≥80% support |
| GO | GO:0006182 Biological Process | cGMP biosynthetic process | 497 / 586 | 84.8% | 95.2% of 522 | ≥80% support |
| GO | GO:0020037 Molecular Function | heme binding | 489 / 586 | 83.5% | 93.7% of 522 | ≥80% support |
| GO | GO:0016849 Molecular Function | phosphorus-oxygen lyase activity | 306 / 586 | 52.2% | 58.6% of 522 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000000030.1 | XP_020629903.1 | guanylate cyclase soluble subunit beta-1-like [Orbicella faveolata] | Q4ZHR9 Guanylate cyclase soluble subunit beta-1 OS=Canis lupus fami | JBrowse |
| Mastigias papua | BRAKERKYLP00000000791.1 | CAH3038999.1 | unnamed protein product, partial [Porites lobata] | P20595 Guanylate cyclase soluble subunit beta-1 OS=Rattus norvegicu | JBrowse |
| Mastigias papua | BRAKERKYLP00000000812.1 | XP_020910243.1 | guanylate cyclase soluble subunit beta-1 [Exaiptasia diaphana] | O02298 Soluble guanylate cyclase gcy-35 OS=Caenorhabditis elegans O | JBrowse |
