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This orthogroup contains 519 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 519 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13217 | PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 | 428 / 519 | 82.5% | 100.0% of 428 | ≥80% support |
| GO | GO:0007266 Biological Process | Rho protein signal transduction | 428 / 519 | 82.5% | 99.8% of 429 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 427 / 519 | 82.3% | 99.5% of 429 | ≥80% support |
| GO | GO:0030139 Cellular Component | endocytic vesicle | 427 / 519 | 82.3% | 99.5% of 429 | ≥80% support |
| GO | GO:0030424 Cellular Component | axon | 427 / 519 | 82.3% | 99.5% of 429 | ≥80% support |
| GO | GO:0043542 Biological Process | endothelial cell migration | 427 / 519 | 82.3% | 99.5% of 429 | ≥80% support |
| Pfam | PF00621 | RhoGEF | 405 / 519 | 78.0% | 99.3% of 408 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 405 / 519 | 78.0% | 94.4% of 429 | ≥50% support |
| KEGG | K19464 | PLEKHG5 — Domain-containing proteins not elsewhere classified | 309 / 519 | 59.5% | 99.4% of 311 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000013608.1 | KAJ7393292.1 | Pleckstrin y domain containing, G (with RhoGef domain) member [Desmophyllum pertusum] | O94827 Pleckstrin homology domain-containing family G member 5 OS=H | JBrowse |
