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This orthogroup contains 466 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 466 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11635 | CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN | 420 / 466 | 90.1% | 100.0% of 420 | ≥80% support |
| Pfam | PF00027 | cNMP_binding — Cyclic nucleotide-binding domain | 417 / 466 | 89.5% | 99.5% of 419 | ≥80% support |
| GO | GO:0005952 Cellular Component | cAMP-dependent protein kinase complex | 419 / 466 | 89.9% | 100.0% of 419 | ≥80% support |
| GO | GO:0004862 Molecular Function | cAMP-dependent protein kinase inhibitor activity | 417 / 466 | 89.5% | 99.5% of 419 | ≥80% support |
| GO | GO:0030552 Molecular Function | cAMP binding | 417 / 466 | 89.5% | 99.5% of 419 | ≥80% support |
| GO | GO:0034236 Molecular Function | protein kinase A catalytic subunit binding | 417 / 466 | 89.5% | 99.5% of 419 | ≥80% support |
| GO | GO:2000480 Biological Process | negative regulation of cAMP-dependent protein kinase activity | 417 / 466 | 89.5% | 99.5% of 419 | ≥80% support |
| KEGG | K04739 | PRKAR — Insulin signaling pathway | 408 / 466 | 87.6% | 100.0% of 408 | ≥80% support |
| Pfam | PF02197 | RIIa — Regulatory subunit of type II PKA R-subunit | 233 / 466 | 50.0% | 55.6% of 419 | ≥50% support |
| GO | GO:0001932 Biological Process | regulation of protein phosphorylation | 363 / 466 | 77.9% | 86.6% of 419 | ≥50% support |
| GO | GO:0008603 Molecular Function | cAMP-dependent protein kinase regulator activity | 363 / 466 | 77.9% | 86.6% of 419 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000003521.1 | CAH3149571.1 | unnamed protein product [Porites lobata] | Q26619 cAMP-dependent protein kinase type II regulatory subunit OS= | JBrowse |
| Mastigias papua | BRAKERKYLP00000014335.1 | XP_041347765.1 | cAMP-dependent protein kinase type II regulatory subunit-like isoform X5 [Gigantopelta aegis] | Q26619 cAMP-dependent protein kinase type II regulatory subunit OS= | JBrowse |
| Mastigias papua | BRAKERKYLP00000016246.1 | CAH3022018.1 | unnamed protein product [Porites evermanni] | Q26619 cAMP-dependent protein kinase type II regulatory subunit OS= | JBrowse |
| Mastigias papua | BRAKERKYLP00000018327.1 | RMX53453.1 | hypothetical protein pdam_00013277 [Pocillopora damicornis] | P00515 cAMP-dependent protein kinase type II-alpha regulatory subun | JBrowse |
