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This orthogroup contains 453 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 453 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46654 | E3 UBIQUITIN-PROTEIN LIGASE HECTD3 | 385 / 453 | 85.0% | 96.5% of 399 | ≥80% support |
| Pfam | PF00632 | HECT | 367 / 453 | 81.0% | 94.6% of 388 | ≥80% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 385 / 453 | 85.0% | 97.5% of 395 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000006255.1 | XP_002154828.3 | E3 ubiquitin-protein ligase HECTD3 [Hydra vulgaris] | Q5T447 E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 G | JBrowse |
| Mastigias papua | BRAKERKYLP00000009326.1 | XP_001628175.3 | uncharacterized protein LOC5507564 isoform X2 [Nematostella vectensis] | Q5T447 E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 G | JBrowse |