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This orthogroup contains 385 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 385 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10480 | PROTEIN UNC-13 HOMOLOG | 330 / 385 | 85.7% | 99.7% of 331 | ≥80% support |
| Pfam | PF00168 | C2 | 313 / 385 | 81.3% | 93.4% of 335 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 330 / 385 | 85.7% | 100.0% of 330 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 330 / 385 | 85.7% | 100.0% of 330 | ≥80% support |
| GO | GO:0017075 Molecular Function | syntaxin-1 binding | 330 / 385 | 85.7% | 100.0% of 330 | ≥80% support |
| GO | GO:0019992 Molecular Function | diacylglycerol binding | 330 / 385 | 85.7% | 100.0% of 330 | ≥80% support |
| GO | GO:0005516 Molecular Function | calmodulin binding | 330 / 385 | 85.7% | 100.0% of 330 | ≥80% support |
| GO | GO:0035249 Biological Process | synaptic transmission, glutamatergic | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0099525 Biological Process | presynaptic dense core vesicle exocytosis | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0098831 Cellular Component | presynaptic active zone cytoplasmic component | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0061789 Biological Process | dense core granule priming | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0043195 Cellular Component | terminal bouton | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0042734 Cellular Component | presynaptic membrane | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0031594 Cellular Component | neuromuscular junction | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0030672 Cellular Component | synaptic vesicle membrane | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0016188 Biological Process | synaptic vesicle maturation | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0016082 Biological Process | synaptic vesicle priming | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0016081 Biological Process | synaptic vesicle docking | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| GO | GO:0007528 Biological Process | neuromuscular junction development | 315 / 385 | 81.8% | 95.5% of 330 | ≥80% support |
| Pfam | PF06292 | MUN | 278 / 385 | 72.2% | 83.0% of 335 | ≥50% support |
| Pfam | PF00130 | C1_1 — Phorbol esters/diacylglycerol binding domain (C1 domain) | 224 / 385 | 58.2% | 66.9% of 335 | ≥50% support |
| KEGG | K15293 | UNC13A_B_C, MUNC13 — Membrane trafficking | 197 / 385 | 51.2% | 96.1% of 205 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000010193.1 | XP_047140160.1 | protein unc-13 homolog A [Hydra vulgaris] | O14795 Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B P | JBrowse |
| Mastigias papua | BRAKERKYLP00000010363.1 | CAF4320370.1 | unnamed protein product, partial [Rotaria magnacalcarata] | Q62769 Protein unc-13 homolog B OS=Rattus norvegicus OX=10116 GN=Un | JBrowse |
