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This orthogroup contains 342 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 342 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22939 | SERINE PROTEASE FAMILY S1C HTRA-RELATED | 277 / 342 | 81.0% | 89.6% of 309 | ≥80% support |
| Pfam | PF13365 | Trypsin_2 — Trypsin-like peptidase domain | 292 / 342 | 85.4% | 94.5% of 309 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 307 / 342 | 89.8% | 99.0% of 310 | ≥80% support |
| GO | GO:0004252 Molecular Function | serine-type endopeptidase activity | 306 / 342 | 89.5% | 98.7% of 310 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 278 / 342 | 81.3% | 89.7% of 310 | ≥80% support |
| Pfam | PF13180 | PDZ_2 — PDZ domain | 221 / 342 | 64.6% | 71.5% of 309 | ≥50% support |
| GO | GO:0012501 Biological Process | programmed cell death | 207 / 342 | 60.5% | 66.8% of 310 | ≥50% support |
| GO | GO:0043065 Biological Process | positive regulation of apoptotic process | 207 / 342 | 60.5% | 66.8% of 310 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000012425.1 | XP_022785888.1 | serine protease HTRA2, mitochondrial-like [Stylophora pistillata] | O43464 Serine protease HTRA2, mitochondrial OS=Homo sapiens OX=9606 | JBrowse |
| Mastigias papua | BRAKERKYLP00000012426.1 | XP_022785888.1 | serine protease HTRA2, mitochondrial-like [Stylophora pistillata] | O43464 Serine protease HTRA2, mitochondrial OS=Homo sapiens OX=9606 | JBrowse |
| Mastigias papua | BRAKERKYLP00000016045.1 | XP_048585176.1 | serine protease HTRA2, mitochondrial-like [Nematostella vectensis] | A9JRB3 Serine protease HTRA1B OS=Danio rerio OX=7955 GN=htra1b PE=2 | JBrowse |
