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This orthogroup contains 306 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 306 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13298 | CYTOSOLIC REGULATOR PIANISSIMO | 256 / 306 | 83.7% | 99.6% of 257 | ≥80% support |
| GO | GO:0031929 Biological Process | TOR signaling | 256 / 306 | 83.7% | 99.6% of 257 | ≥80% support |
| GO | GO:0031932 Cellular Component | TORC2 complex | 256 / 306 | 83.7% | 99.6% of 257 | ≥80% support |
| GO | GO:0038203 Biological Process | TORC2 signaling | 256 / 306 | 83.7% | 99.6% of 257 | ≥80% support |
| GO | GO:0043539 Molecular Function | protein serine/threonine kinase activator activity | 254 / 306 | 83.0% | 98.8% of 257 | ≥80% support |
| GO | GO:0051897 Biological Process | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | 254 / 306 | 83.0% | 98.8% of 257 | ≥80% support |
| Pfam | PF14664 | RICTOR_N — Rapamycin-insensitive companion of mTOR, N-term | 207 / 306 | 67.7% | 81.8% of 253 | ≥50% support |
| Pfam | PF14668 | RICTOR_V — Rapamycin-insensitive companion of mTOR, domain 5 | 206 / 306 | 67.3% | 81.4% of 253 | ≥50% support |
| Pfam | PF14666 | RICTOR_M — Rapamycin-insensitive companion of mTOR, middle domain | 205 / 306 | 67.0% | 81.0% of 253 | ≥50% support |
| Pfam | PF14663 | RasGEF_N_2 — Rapamycin-insensitive companion of mTOR RasGEF_N domain | 204 / 306 | 66.7% | 80.6% of 253 | ≥50% support |
| KEGG | K08267 | RICTOR — Membrane trafficking | 175 / 306 | 57.2% | 99.4% of 176 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000006222.1 | XP_047128439.1 | rapamycin-insensitive companion of mTOR-like [Hydra vulgaris] | Q6QI06 Rapamycin-insensitive companion of mTOR OS=Mus musculus OX=1 | JBrowse |