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This orthogroup contains 297 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 297 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43172 | ADENYLOSUCCINATE LYASE | 273 / 297 | 91.9% | 99.6% of 274 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 272 / 297 | 91.6% | 99.3% of 274 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 271 / 297 | 91.3% | 98.9% of 274 | ≥80% support |
| GO | GO:0004018 Molecular Function | N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity | 270 / 297 | 90.9% | 98.5% of 274 | ≥80% support |
| GO | GO:0044208 Biological Process | 'de novo' AMP biosynthetic process | 270 / 297 | 90.9% | 98.5% of 274 | ≥80% support |
| GO | GO:0070626 Molecular Function | (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity | 270 / 297 | 90.9% | 98.5% of 274 | ≥80% support |
| Pfam | PF10397 | ADSL_C — Adenylosuccinate lyase C-terminus | 233 / 297 | 78.5% | 90.7% of 257 | ≥50% support |
| Pfam | PF00206 | Lyase_1 — Lyase | 230 / 297 | 77.4% | 89.5% of 257 | ≥50% support |
| GO | GO:0009152 Biological Process | purine ribonucleotide biosynthetic process | 181 / 297 | 60.9% | 66.1% of 274 | ≥50% support |
| KEGG | K01756 | purB, ADSL — Alanine, aspartate and glutamate metabolism | 184 / 297 | 62.0% | 97.4% of 189 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000025916.1 | XP_020611069.1 | adenylosuccinate lyase-like isoform X1 [Orbicella faveolata] | P21265 Adenylosuccinate lyase OS=Gallus gallus OX=9031 GN=ADSL PE=2 | JBrowse |
