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This orthogroup contains 295 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 295 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45670 | E3 UBIQUITIN-PROTEIN LIGASE TRIP12 | 253 / 295 | 85.8% | 96.6% of 262 | ≥80% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 253 / 295 | 85.8% | 96.9% of 261 | ≥80% support |
| GO | GO:0006511 Biological Process | ubiquitin-dependent protein catabolic process | 253 / 295 | 85.8% | 96.9% of 261 | ≥80% support |
| GO | GO:0016607 Cellular Component | nuclear speck | 253 / 295 | 85.8% | 96.9% of 261 | ≥80% support |
| GO | GO:0043161 Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | 253 / 295 | 85.8% | 96.9% of 261 | ≥80% support |
| GO | GO:0048856 Biological Process | anatomical structure development | 253 / 295 | 85.8% | 96.9% of 261 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 253 / 295 | 85.8% | 96.9% of 261 | ≥80% support |
| GO | GO:0070534 Biological Process | protein K63-linked ubiquitination | 253 / 295 | 85.8% | 96.9% of 261 | ≥80% support |
| Pfam | PF00632 | HECT | 197 / 295 | 66.8% | 80.1% of 246 | ≥50% support |
| Pfam | PF18410 | BTHB — Basic tilted helix bundle domain | 193 / 295 | 65.4% | 78.5% of 246 | ≥50% support |
| Pfam | PF07738 | Sad1_UNC — Sad1 / UNC-like C-terminal | 189 / 295 | 64.1% | 76.8% of 246 | ≥50% support |
| Pfam | PF12796 | Ank_2 — Ankyrin repeats (3 copies) | 189 / 295 | 64.1% | 76.8% of 246 | ≥50% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 226 / 295 | 76.6% | 86.6% of 261 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 194 / 295 | 65.8% | 74.3% of 261 | ≥50% support |
| KEGG | K12231 | HECTD1 — Ubiquitin system | 166 / 295 | 56.3% | 97.7% of 170 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000017929.1 | XP_047133370.1 | E3 ubiquitin-protein ligase HECTD1 isoform X2 [Hydra vulgaris] | Q9ULT8 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 G | JBrowse |
