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This orthogroup contains 283 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 283 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22957 | TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN | 227 / 283 | 80.2% | 99.6% of 228 | ≥80% support |
| Pfam | PF00566 | RabGAP-TBC — Rab-GTPase-TBC domain | 228 / 283 | 80.6% | 93.4% of 244 | ≥80% support |
| GO | GO:0005096 Molecular Function | GTPase activator activity | 228 / 283 | 80.6% | 99.6% of 229 | ≥80% support |
| GO | GO:0090630 Biological Process | activation of GTPase activity | 227 / 283 | 80.2% | 99.1% of 229 | ≥80% support |
| Pfam | PF12068 | PH_RBD — Rab-binding domain (RBD) | 223 / 283 | 78.8% | 91.4% of 244 | ≥50% support |
| Pfam | PF02759 | RUN | 217 / 283 | 76.7% | 88.9% of 244 | ≥50% support |
| KEGG | K21847 | SGSM1, RUTBC2 — Membrane trafficking | 169 / 283 | 59.7% | 97.1% of 174 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000024354.1 | XP_012554607.2 | small G protein signaling modulator 1 [Hydra vulgaris] | Q8BPQ7 Small G protein signaling modulator 1 OS=Mus musculus OX=100 | JBrowse |
