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This orthogroup contains 262 genes from 135 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 262 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10848 | MEIOTIC RECOMBINATION PROTEIN SPO11 | 216 / 262 | 82.4% | 99.5% of 217 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 216 / 262 | 82.4% | 99.1% of 218 | ≥80% support |
| GO | GO:0003918 Molecular Function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | 216 / 262 | 82.4% | 99.1% of 218 | ≥80% support |
| GO | GO:0005694 Cellular Component | chromosome | 216 / 262 | 82.4% | 99.1% of 218 | ≥80% support |
| GO | GO:0000228 Cellular Component | nuclear chromosome | 215 / 262 | 82.1% | 98.6% of 218 | ≥80% support |
| GO | GO:0000706 Biological Process | meiotic DNA double-strand break processing | 215 / 262 | 82.1% | 98.6% of 218 | ≥80% support |
| GO | GO:0007131 Biological Process | reciprocal meiotic recombination | 215 / 262 | 82.1% | 98.6% of 218 | ≥80% support |
| GO | GO:0042138 Biological Process | meiotic DNA double-strand break formation | 215 / 262 | 82.1% | 98.6% of 218 | ≥80% support |
| Pfam | PF21180 | TOP6A-Spo11_Toprim — Topoisomerase 6 subunit A/Spo11, Toprim domain | 201 / 262 | 76.7% | 92.6% of 217 | ≥50% support |
| Pfam | PF04406 | TP6A_N — Type IIB DNA topoisomerase | 166 / 262 | 63.4% | 76.5% of 217 | ≥50% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 166 / 262 | 63.4% | 76.2% of 218 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 166 / 262 | 63.4% | 76.2% of 218 | ≥50% support |
| GO | GO:0006259 Biological Process | DNA metabolic process | 166 / 262 | 63.4% | 76.2% of 218 | ≥50% support |
| KEGG | K10878 | SPO11 — Chromosome and associated proteins | 147 / 262 | 56.1% | 98.7% of 149 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000009026.1 | XP_049832715.1 | meiotic recombination protein SPO11-like [Schistocerca gregaria] | Q9Y5K1 Meiotic recombination protein SPO11 OS=Homo sapiens OX=9606 | JBrowse |
