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This orthogroup contains 253 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 253 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11347 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE | 203 / 253 | 80.2% | 99.0% of 205 | ≥80% support |
| GO | GO:0004114 Molecular Function | 3',5'-cyclic-nucleotide phosphodiesterase activity | 204 / 253 | 80.6% | 99.5% of 205 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 204 / 253 | 80.6% | 99.5% of 205 | ≥80% support |
| GO | GO:0048101 Molecular Function | calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity | 203 / 253 | 80.2% | 99.0% of 205 | ≥80% support |
| Pfam | PF00233 | PDEase_I — 3'5'-cyclic nucleotide phosphodiesterase | 202 / 253 | 79.8% | 99.0% of 204 | ≥50% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 201 / 253 | 79.5% | 98.1% of 205 | ≥50% support |
| KEGG | K19021 | PDE3A — Morphine addiction | 177 / 253 | 70.0% | 98.3% of 180 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000016444.1 | XP_047122957.1 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X6 [Hydra vulgaris] | Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A OS=Homo sap | JBrowse |