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This orthogroup contains 253 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 253 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13152 | TFIIH, POLYPEPTIDE 4 | 228 / 253 | 90.1% | 100.0% of 228 | ≥80% support |
| Pfam | PF03849 | Tfb2 | 230 / 253 | 90.9% | 100.0% of 230 | ≥80% support |
| GO | GO:0000439 Cellular Component | transcription factor TFIIH core complex | 230 / 253 | 90.9% | 100.0% of 230 | ≥80% support |
| GO | GO:0001671 Molecular Function | ATPase activator activity | 230 / 253 | 90.9% | 100.0% of 230 | ≥80% support |
| GO | GO:0006289 Biological Process | nucleotide-excision repair | 230 / 253 | 90.9% | 100.0% of 230 | ≥80% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 228 / 253 | 90.1% | 99.1% of 230 | ≥80% support |
| GO | GO:0005675 Cellular Component | transcription factor TFIIH holo complex | 228 / 253 | 90.1% | 99.1% of 230 | ≥80% support |
| GO | GO:0070816 Biological Process | obsolete phosphorylation of RNA polymerase II C-terminal domain | 228 / 253 | 90.1% | 99.1% of 230 | ≥80% support |
| Pfam | PF18307 | Tfb2_C — Transcription factor Tfb2 (p52) C-terminal domain | 191 / 253 | 75.5% | 83.0% of 230 | ≥50% support |
| KEGG | K03144 | TFIIH4, GTF2H4, TFB2 — DNA repair and recombination proteins | 175 / 253 | 69.2% | 99.4% of 176 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000007203.1 | XP_020626918.1 | general transcription factor IIH subunit 4-like isoform X1 [Orbicella faveolata] | Q92759 General transcription factor IIH subunit 4 OS=Homo sapiens O | JBrowse |
