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This orthogroup contains 252 genes from 135 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 252 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 205 / 252 | 81.4% | 99.0% of 207 | ≥80% support |
| PANTHER | PTHR24348 | SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED | 194 / 252 | 77.0% | 98.5% of 197 | ≥50% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 194 / 252 | 77.0% | 91.9% of 211 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 196 / 252 | 77.8% | 94.7% of 207 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 195 / 252 | 77.4% | 94.2% of 207 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 195 / 252 | 77.4% | 94.2% of 207 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 195 / 252 | 77.4% | 94.2% of 207 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 195 / 252 | 77.4% | 94.2% of 207 | ≥50% support |
| GO | GO:0005776 Cellular Component | autophagosome | 194 / 252 | 77.0% | 93.7% of 207 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 194 / 252 | 77.0% | 93.7% of 207 | ≥50% support |
| GO | GO:0010506 Biological Process | regulation of autophagy | 194 / 252 | 77.0% | 93.7% of 207 | ≥50% support |
| GO | GO:0000045 Biological Process | autophagosome assembly | 194 / 252 | 77.0% | 93.7% of 207 | ≥50% support |
| GO | GO:0018105 Biological Process | peptidyl-serine phosphorylation | 194 / 252 | 77.0% | 93.7% of 207 | ≥50% support |
| GO | GO:0046777 Biological Process | protein autophosphorylation | 194 / 252 | 77.0% | 93.7% of 207 | ≥50% support |
| GO | GO:0000407 Cellular Component | phagophore assembly site | 194 / 252 | 77.0% | 93.7% of 207 | ≥50% support |
| GO | GO:0034045 Cellular Component | phagophore assembly site membrane | 191 / 252 | 75.8% | 92.3% of 207 | ≥50% support |
| GO | GO:0034727 Biological Process | piecemeal microautophagy of the nucleus | 191 / 252 | 75.8% | 92.3% of 207 | ≥50% support |
| GO | GO:0042594 Biological Process | response to starvation | 191 / 252 | 75.8% | 92.3% of 207 | ≥50% support |
| GO | GO:0044805 Biological Process | obsolete late nucleophagy | 191 / 252 | 75.8% | 92.3% of 207 | ≥50% support |
| GO | GO:0061709 Biological Process | reticulophagy | 191 / 252 | 75.8% | 92.3% of 207 | ≥50% support |
| GO | GO:0000422 Biological Process | autophagy of mitochondrion | 191 / 252 | 75.8% | 92.3% of 207 | ≥50% support |
| KEGG | K08269 | ULK2, ATG1 — Mitochondrial biogenesis | 128 / 252 | 50.8% | 97.7% of 131 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000024182.1 | XP_047142751.1 | serine/threonine-protein kinase unc-51 [Hydra vulgaris] | Q8IYT8 Serine/threonine-protein kinase ULK2 OS=Homo sapiens OX=9606 | JBrowse |