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This orthogroup contains 213 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 213 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22748 | AP ENDONUCLEASE | 182 / 213 | 85.5% | 100.0% of 182 | ≥80% support |
| Pfam | PF03372 | Exo_endo_phos — Endonuclease/Exonuclease/phosphatase family | 173 / 213 | 81.2% | 94.5% of 183 | ≥80% support |
| GO | GO:0003906 Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | 182 / 213 | 85.5% | 96.8% of 188 | ≥80% support |
| GO | GO:0004518 Molecular Function | nuclease activity | 182 / 213 | 85.5% | 96.8% of 188 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 182 / 213 | 85.5% | 96.8% of 188 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 182 / 213 | 85.5% | 96.8% of 188 | ≥80% support |
| GO | GO:0006284 Biological Process | base-excision repair | 182 / 213 | 85.5% | 96.8% of 188 | ≥80% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 182 / 213 | 85.5% | 96.8% of 188 | ≥80% support |
| GO | GO:0008311 Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | 182 / 213 | 85.5% | 96.8% of 188 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 173 / 213 | 81.2% | 92.0% of 188 | ≥80% support |
| Pfam | PF06839 | zf-GRF — GRF zinc finger | 165 / 213 | 77.5% | 90.2% of 183 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 166 / 213 | 77.9% | 88.3% of 188 | ≥50% support |
| KEGG | K10772 | APEX2 — DNA repair and recombination proteins | 158 / 213 | 74.2% | 99.4% of 159 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000015854.1 | XP_019627669.1 | PREDICTED: DNA-(apurinic or apyrimidinic site) lyase 2-like isoform X2 [Branchiostoma belcheri] | Q6DDT4 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Xenopu | JBrowse |
