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This orthogroup contains 204 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 204 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12358 | SPHINGOSINE KINASE | 175 / 204 | 85.8% | 99.4% of 176 | ≥80% support |
| Pfam | PF00781 | DAGK_cat — Diacylglycerol kinase catalytic domain | 166 / 204 | 81.4% | 94.9% of 175 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 176 / 204 | 86.3% | 98.3% of 179 | ≥80% support |
| GO | GO:0001727 Molecular Function | lipid kinase activity | 175 / 204 | 85.8% | 97.8% of 179 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 175 / 204 | 85.8% | 97.8% of 179 | ≥80% support |
| GO | GO:0006665 Biological Process | sphingolipid metabolic process | 175 / 204 | 85.8% | 97.8% of 179 | ≥80% support |
| GO | GO:0016310 Biological Process | phosphorylation | 175 / 204 | 85.8% | 97.8% of 179 | ≥80% support |
| GO | GO:0043231 Cellular Component | intracellular membrane-bounded organelle | 175 / 204 | 85.8% | 97.8% of 179 | ≥80% support |
| GO | GO:0046512 Biological Process | sphingosine biosynthetic process | 175 / 204 | 85.8% | 97.8% of 179 | ≥80% support |
| GO | GO:0016301 Molecular Function | kinase activity | 174 / 204 | 85.3% | 97.2% of 179 | ≥80% support |
| GO | GO:0017050 Molecular Function | D-erythro-sphingosine kinase activity | 173 / 204 | 84.8% | 96.7% of 179 | ≥80% support |
| Pfam | PF19279 | YegS_C — YegS C-terminal NAD kinase beta sandwich-like domain | 138 / 204 | 67.7% | 78.9% of 175 | ≥50% support |
| KEGG | K04718 | SPHK — Tuberculosis | 159 / 204 | 77.9% | 98.2% of 162 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000026003.1 | XP_032236955.1 | sphingosine kinase 1 [Nematostella vectensis] | Q9JIA7 Sphingosine kinase 2 OS=Mus musculus OX=10090 GN=Sphk2 PE=1 | JBrowse |
