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This orthogroup contains 162 genes from 132 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 162 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR21199 | COMM DOMAIN-CONTAINING PROTEIN 1 | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| Pfam | PF17221 | COMMD1_N — COMMD1 N-terminal domain | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| Pfam | PF07258 | COMM_domain — COMM domain | 138 / 162 | 85.2% | 96.5% of 143 | ≥80% support |
| GO | GO:0005768 Cellular Component | endosome | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| GO | GO:0031398 Biological Process | positive regulation of protein ubiquitination | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| GO | GO:0032434 Biological Process | regulation of proteasomal ubiquitin-dependent protein catabolic process | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| GO | GO:0055070 Biological Process | copper ion homeostasis | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| GO | GO:1902306 Biological Process | negative regulation of sodium ion transmembrane transport | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| GO | GO:2000009 Biological Process | negative regulation of protein localization to cell surface | 142 / 162 | 87.7% | 99.3% of 143 | ≥80% support |
| KEGG | K22557 | COMMD1, MURR1 — Ubiquitin system | 135 / 162 | 83.3% | 99.3% of 136 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Mastigias papua | BRAKERKYLP00000017380.1 | XP_020603519.1 | COMM domain-containing protein 1-like isoform X1 [Orbicella faveolata] | Q8K4M5 COMM domain-containing protein 1 OS=Mus musculus OX=10090 GN | JBrowse |